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ea0056p188 | Bone ' Osteoporosis | ECE2018

Bone mineral density decline following denosumab discontinuation might not be attenuated with previous bisphosphonate therapy

Japelj Miha , Vidmar Gaj , Rajic Antonela Sabati , Pfeifer Marija , Kocjan Tomaz

Objective: Limited data suggest that the rebound increase in bone resorption and rapid bone mineral density (BMD) decline following sudden interruption of denosumab therapy can be avoided in patients previously treated with bisphosphonates. We aimed to compare BMD changes in osteoporotic patients after denosumab discontinuation regarding their previous bisphosphonate (BP) therapy.Material and methods: There were 14 women (age 69 years, BMI 23.1 kg/m...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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